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Rekombinant Anti-Bcl6 Antikörper [BCL6/8983R] (A315876)

$765

Monoklonal [BCL6/8983R] Kaninchen Antikörper gegen Bcl6 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Bcl6 Antibody [BCL6/8983R] - BSA and Azide free
Beschreibung
Recombinant rabbit monoclonal [BCL6/8983R] antibody to Bcl6.
Spezifität
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Anwendungen
IHC-P
Positivkontrolle
Raji or Ramos cells. Human tonsil or Hodgkin s lymphoma.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (aa1-400) of human BCL6 protein. The exact sequence is proprietary.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
BCL6/8983R
Isotyp
IgG
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
95 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
B cell CLL/lymphoma 6, B cell lymphoma 6 protein, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein, BCL 5, Bcl 6, BCL-5, BCL-6, BCL5, BCL6A, BCL6_HUMAN, cys his2 zinc finger transcription factor, LAZ 3, LAZ 3 protein, LAZ3, Lymphoma associated zinc finger gene on chromosome 3, Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3), Protein LAZ-3, ZBTB 27, ZBTB27, Zinc finger and BTB domain containing protein 27, Zinc finger and BTB domain-containing protein 27, Zinc finger and BTB domain-containing protein 27 (ZBTB27), Zinc finger protein 51, Zinc Finger Protein 51 (ZNF51), zinc finger transcription factor BCL6S, ZNF 51, ZNF51
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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