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Anti-B7H4 Antikörper [B7H4/1788] (A250377)

Monoklonal [B7H4/1788] Maus Antikörper gegen B7H4 für ELISA, Flow Cytometry, IF, WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-B7H4 Antibody [B7H4/1788]
Beschreibung
Mouse monoclonal [B7H4/1788] antibody to B7H4.
Spezifität
T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer.
Anwendungen
ELISA, Flow Cytometry, IF, WB, IHC-P
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment of human B7-H4 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
B7H4/1788
Isotyp
IgG2a
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
35 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-B7H4 Antibody [B7H4/1788] - BSA and Azide free (A253557).
Synonyme
B7 family member, H4, B7 H4, B7 homolog 4, B7 superfamily member 1, B7 superfamily, member 1, B7-H4, B7h.5, B7S1, B7x, BC032925, Immune costimulatory protein B7-H4, Immune costimulatory protein B7H4, MGC41287, PRO1291, Protein B7S1, RP11 229A19.4, T cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, V set domain-containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, VCTN1, Vtcn1, VTCN1_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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