Rekombinant Anti-Aurora B Antikörper [rAURKB/1592] (A250526)

Name: Anti-Aurora B Antibody [rAURKB/1592]
Brand: Antibodies.com
SKU: A250526
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [rAURKB/1592] Maus Antikörper gegen Aurora B für IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

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+1 (314) 370-6046

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Stichworte:

Rekombinant Antikörper

Produktdetails

Produktname

Anti-Aurora B Antibody [rAURKB/1592]

Beschreibung

Recombinant mouse monoclonal [rAURKB/1592] antibody to Aurora B.

Spezifität

This antibody recognizes a protein of 39kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.

Anwendungen

IHC-P

Verdünnungen

IHC-P: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant fragment, around amino acids 89-251, of human Aurora B protein. The exact sequence is proprietary.

Wirt

Mouse

Klonalität

Monoclonal

Klon

rAURKB/1592

Isotyp

IgG1

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

200 µg/ml

Molekulargewicht

39 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Aurora B Antibody [rAURKB/1592] - BSA and Azide free (A253706).

Synonyme

AIK2, AIM-1, AIM1, ARK-2, ARK2, AurB, AURKB, AURKB_HUMAN, Aurora 1, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora related kinase 2, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora-related kinase 2, Aurora/IPL1 related kinase 2, Aurora/IPL1-related kinase 2, IPL1, PPP1R48, Protein phosphatase 1 regulatory subunit 48, Serine/theronine kinase 12, Serine/threonine protein kinase 12, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase aurora-B, STK-1, STK1, STK12, STK5

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (4)

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Figure 1: Immunohistochemistry - Anti-Aurora B Antibody [rAURKB/1592] (A250526)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney using Anti-Aurora B Antibody [rAURKB/1592].

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Figure 2: Immunohistochemistry - Anti-Aurora B Antibody [rAURKB/1592] (A250526)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney using Anti-Aurora B Antibody [rAURKB/1592].

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Figure 3: Immunohistochemistry - Anti-Aurora B Antibody [rAURKB/1592] (A250526)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human placenta using Anti-Aurora B Antibody [rAURKB/1592].

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Figure 4: SDS-PAGE - Anti-Aurora B Antibody [rAURKB/1592] (A250526)

SDS-PAGE analysis of Anti-Aurora B Antibody [rAURKB/1592] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.