Anti-ATRX Antibody [ATRX/7940] - BSA and Azide free (A315866)

Anti-ATRX Antibody [ATRX/7940] - BSA and Azide free

Mouse monoclonal [ATRX/7940] antibody to ATRX.

ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome

Human pancreas, adrenal, ovary, kidney, prostate or stomach.

IHC: 1-2 µg/ml

Human

Recombinant full-length human ATRX protein.

Mouse

Monoclonal

ATRX/7940

Protein A/G chromatography.

1 mg/ml

280 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ATP-dependent helicase ATRX, RAD54L, Transcriptional regulator ATRX, X-linked helicase II, X-linked nuclear protein, XH2, XNP, Znf-HX