Recombinant rabbit monoclonal [ARG1/6790R] antibody to Arginase 1.
Spezifität
This antibody recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Anwendungen
WB, IHC
Verdünnungen
WB: 2-4 µg/ml, IHC-P: 2-4 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 300-400, of human Arginase 1. The exact sequence is proprietary.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
ARG1/6790R
Isotyp
IgG
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
35-38 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
A I, Al, ARG 1, arg1, ARGI1_HUMAN, Arginase liver, Arginase type I, Arginase, liver, Arginase-1, Arginase1, Liver Arginase, Liver type arginase, Liver-type arginase, Type I arginase