Rekombinant Anti-AMACR Antikörper [rAMACR/4674] (A251794)

Name: Anti-AMACR Antibody [rAMACR/4674] - BSA and Azide free
Brand: Antibodies.com
SKU: A251794
Price: 525.0 USD
Availability: InStock

Bild Vergrößern

$525

Monoklonal [rAMACR/4674] Maus Antikörper gegen AMACR für IHC-P.

100% Qualitätsgarantie

Preis-Match-Garantie

Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

orders@antibodies.com

Garantien

100% Qualitätsgarantie

Preis-Match-Garantie

Stichworte:

Rekombinant Antikörper

Produktdetails

Produktname

Anti-AMACR Antibody [rAMACR/4674] - BSA and Azide free

Beschreibung

Recombinant mouse monoclonal [rAMACR/4674] antibody to AMACR.

Spezifität

This antibody recognizes a protein of 42kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

Anwendungen

IHC-P

Verdünnungen

IHC-P: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant full-length human AMACR protein.

Wirt

Mouse

Klonalität

Monoclonal

Klon

rAMACR/4674

Isotyp

IgG2a

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

1 mg/ml

Molekulargewicht

42 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-AMACR Antibody [rAMACR/4674] (A248612).

Synonyme

2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl-CoA racemase deficiency, included, Alpha-methylacyl-CoA racemase, AMACR deficiency, included, AMACR_HUMAN, CBAS4, Da1-8, EC 5.1.99.4, Macr1, Methylacyl CoA racemase alpha, RACE, RM

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (2)

Bild Vergrößern

Figure 1: Immunohistochemistry - Anti-AMACR Antibody [rAMACR/4674] - BSA and Azide free (A251794)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate carcinoma using Anti-AMACR Antibody [rAMACR/4674].

Bild Vergrößern

Figure 2: SDS-PAGE - Anti-AMACR Antibody [rAMACR/4674] - BSA and Azide free (A251794)

SDS-PAGE analysis of Anti-AMACR Antibody [rAMACR/4674] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.