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Rekombinant Anti-AMACR Antikörper [rAMACR/1864] (A248611)

Monoklonal [rAMACR/1864] Maus Antikörper gegen AMACR für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-AMACR Antibody [rAMACR/1864]
Beschreibung
Recombinant mouse monoclonal [rAMACR/1864] antibody to AMACR.
Spezifität
This antibody recognizes a protein of 42kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
Anwendungen
WB, IHC-P
Verdünnungen
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 297-394, of human AMACR protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rAMACR/1864
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
42 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-AMACR Antibody [rAMACR/1864] - BSA and Azide free (A251793).
Synonyme
2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl-CoA racemase deficiency, included, Alpha-methylacyl-CoA racemase, AMACR deficiency, included, AMACR_HUMAN, CBAS4, Da1-8, EC 5.1.99.4, Macr1, Methylacyl CoA racemase alpha, RACE, RM
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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