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Anti-alpha Fodrin Antikörper [SPTAN1/3351] (A250040)

Monoklonal [SPTAN1/3351] Maus Antikörper gegen alpha Fodrin für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-alpha Fodrin Antibody [SPTAN1/3351]
Beschreibung
Mouse monoclonal [SPTAN1/3351] antibody to alpha Fodrin.
Spezifität
Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 2351-2475, of human SPTAN1 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
SPTAN1/3351
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
240 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-alpha Fodrin Antibody [SPTAN1/3351] - BSA and Azide free (A253220).
Synonyme
(ALPHA)II-SPECTRIN, Alpha II Spectrin, Alpha-II spectrin, brain, EIEE5, FLJ17738, FLJ44613, Fodrin alpha chain, Fodrin, alpha, NEAS, Non erythrocytic spectrin alpha, non-erythroid alpha chain, SPECA, Spectrin, Spectrin alpha chain, Spectrin alpha chain brain, Spectrin alpha non erythrocytic 1, Spectrin non erythroid alpha chain, Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spectrin, nonerythroid, alpha subunit, Spna2, SPTA 2, SPTA2, SPTA2_HUMAN, SPTAN 1, SPTAN1
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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