+1 (314) 370-6046 oderKontakt

Anti-ALDH1L1 Antikörper [ALDH1L1/7702] (A315826)

$765

Monoklonal [ALDH1L1/7702] Maus Antikörper gegen ALDH1L1 für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-ALDH1L1 Antibody [ALDH1L1/7702] - BSA and Azide free
Beschreibung
Mouse monoclonal [ALDH1L1/7702] antibody to ALDH1L1.
Spezifität
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1L1 (aldehyde dehydrogenase 1 family member L1), also known as FTHFD or 10-FTHFD (10-formyltetrahydrofolate dehydrogenase), is a cytosolic protein that is developmentally regulated in the cerebellum. ALDH1L1 binds to folate and catalyzes the conversion of 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF). This suggests a possible role for ALDH1L1 in the regulation of cellular THF levels as well as in the inhibition of cell proliferation (as 10-FTHF is essential for the synthesis of purine). In addition, the overexpression of ALDH1L1 can restrict cell proliferation in vitro.
Anwendungen
WB, IHC-P
Positivkontrolle
Human kidney or liver. A549 or SK-BR3 cells.
Verdünnungen
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment of human ALDH1L1 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
ALDH1L1/7702
Isotyp
IgG
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
99 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
10 formyltetrahydrofolate dehydrogenase, 10 FTHFDH, 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, AL1L1_HUMAN, Aldehyde dehydrogenase 1 family member L1, Aldehyde dehydrogenase family 1 member L1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, DKFZp781N0997, EC 1.5.1.6, FDH, formyltetrahydrofolate dehydrogenase, FTHFD, OTTHUMP00000155221, OTTHUMP00000214696, OTTHUMP00000214700, OTTHUMP00000222724
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Alternative Produkte zum Anti-ALDH1L1 Antikörper [ALDH1L1/7702] (A315826)

Oben