Recombinant Anti-Cytokeratin 17 Antibody [KRT17/7155R] - BSA and Azide free (A278607)

Recombinant rabbit monoclonal [KRT17/7155R] antibody to Cytokeratin 17 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Cytokeratin 17 Antibody [KRT17/7155R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [KRT17/7155R] antibody to Cytokeratin 17.
Specificity
Cytokeratin 17 (CK17) is normally expressed in the basal cells ofcomplex epithelia but not in stratified orsimple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glandssuch as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. Additionally, anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human Cytokeratin 17.
Host
Rabbit
Clonality
Monoclonal
Clone ID
KRT17/7155R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
46 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Cytokeratin 17 Antibody [KRT17/7155R] (A278019).
Synonyms
39.1, CK 17, CK-17, Cytokeratin-17, K17, K1C17_HUMAN, Keratin, Keratin 17, keratin 17 epitope S1, keratin 17 epitope S2, keratin 17 epitope S4, Keratin 17, type I, Keratin type I cytoskeletal 17, keratin, type i cytoskeletal 17 [version 1], Keratin-17, KRT17, PC, PC2, PCHC1, type I cytoskeletal 17
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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