Anti-Cytochrome p450 Antibody [M12P4H2] (A248314)

Anti-Cytochrome p450 Antibody [M12P4H2]

Mouse monoclonal [M12P4H2] antibody to Cytochrome p450.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

IHC-P: 1-2 µg/ml

Human

Synthetic peptide from the C terminal of Cytochrome p450 protein, conjugated to Ovalbumin.

HIGFGCIPPR

Mouse

Monoclonal

M12P4H2

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

~50-55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Cytochrome p450 Antibody [M12P4H2] - BSA and Azide free (A251496).

4 nitrophenol 2 hydroxylase, CPE 1, CPE1, CYP2E, CYP2E1, CYPIIE1, Cytochrome P450 2E1, Cytochrome P450 family 2 subfamily E polypeptide 1, Cytochrome P450 J, Cytochrome P450 subfamily IIE (ethanol inducible) polypeptide 1, Cytochrome P450 subfamily IIE polypeptide 1, Flavoprotein linked monooxygenase, Microsomal monooxygenase, OTTHUMP00000046571, p450, P450 J, P450C2E, Xenobiotic monooxygenase