Anti-CXCL9 Antibody - BSA and Azide free (A283251)

Anti-CXCL9 Antibody - BSA and Azide free

Rabbit polyclonal antibody to CXCL9.

This antibody recognises human CXCL9, otherwise known as MIG (monokine induced by Interferon-gamma), a member of the CXC family of chemokine receptors, secreted by interferon stimulated monocytes, macrophages and endothelial cells. CXCL9 signals through binding to CD183 (CXCR3).CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant, and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumou growth inhibition and angiogenesis. CXCL9 is active against E.coli, S.aureus, L.monocytogenes and S.pyogenes.

WB, ELISA, IHC-P, Functional Assays

ELISA: 0.5 - 2 µg/ml, Functional Assays: 5.0 - 7.0 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human CXCL9.

Rabbit

Polyclonal

IgG

1 mg/ml after reconstitution.

Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human CXCL9 polyclonal antinbody recognizes human CXCL9, otherwise known as MIG (monokine induced by Interferon-gamma), a member of the CXC family of chemokine receptors, secreted by interferon stimulated monocytes, macrophages (Muller et al. 2010) and endothelial cells (Loos et al. 2006). CXCL9 signals through binding to CD183 (CXCR3).CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant, and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumou growth inhibition and angiogenesis (Whiting et al. 2004) . CXCL9 is active against E.coli, S.aureus, L.monocytogenes (Cole et al. 2001) and S.pyogenes (Egesten et al. 2007).

C-X-C motif chemokine 9, CMK, Gamma-interferon-induced monokine, HuMIG, MIG, Monokine induced by interferon-gamma, SCYB9, Small-inducible cytokine B9