Anti-Creatine Kinase MB Antibody [CKBB/6566] (A314816)

Anti-Creatine Kinase MB Antibody [CKBB/6566]

Mouse monoclonal [CKBB/6566] antibody to Creatine Kinase MB.

Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB. This MAb recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB.

ELISA, WB, IHC-P

SH-SY5Y or HEK-293 cells. Human cerebellum.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant human full-length CKB protein.

Mouse

Monoclonal

CKBB/6566

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

42 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

B-CK, brain creatine kinase, CKBB, CKMB, CKMM, creatine kinase B, creatine kinase brain, creatine kinase M, creatine kinase muscle, M-CK, muscle creatine kinase