Anti-Clostridium difficile Toxin A Antibody [5155] (A278813)

Anti-Clostridium difficile Toxin A Antibody [5155]

Mouse monoclonal [5155] antibody to Clostridium difficile Toxin A.

This antibody recognises Clostridium difficile toxin A. No reaction is observed with Clostridium difficile toxin B, tetanus toxoid, Pseudomonas aeruginosa and Yersinia enterocoliticaClostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular mass of ~308 kDa and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.

ELISA: 1:20 - 1:200

Bacterial

Clostridium difficile toxin A.

Mouse

Monoclonal

5155

IgG1

Unconjugated

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Clostridium dificile toxin A antibody, clone 5155 recognizes Clostridium difficile toxin A. No reaction is observed with Clostridium difficile toxin B, tetanus toxoid, Pseudomonas aeruginosa and Yersinia enterocoliticaClostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular mass of ~308 kDa and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.

tcdA, toxA