Anti-Clathrin Light Chain Antibody [SPM174] (A248226)

Anti-Clathrin Light Chain Antibody [SPM174]

Mouse monoclonal [SPM174] antibody to Clathrin Light Chain.

This antibody recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant N terminal fragment of human Clathrin Light Chain.

Mouse

Monoclonal

SPM174

IgG2b

kappa

Protein A/G chromatography.

200 µg/ml

31-44 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Clathrin Light Chain Antibody [SPM174] - BSA and Azide free (A251409).

Clathrin light chain A, Clathrin light chain B, Clathrin light chain LCA, Clathrin light chain LCB, Clathrin light polypeptide, Clathrin light polypeptide A, Clathrin light polypeptide B, Clathrin light polypeptide LCA, Clathrin light polypeptide LCB, Clathrin, light chain (Lcb), Clathrin, light polypeptide (Lca), Clathrin, light polypeptide (Lcb), CLCA_HUMAN, CLTA, CLTB, Lca, LCB