Anti-CELA3B Antibody [CELA3B/1758] (A248600)

Mouse monoclonal [CELA3B/1758] antibody to CELA3B for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CELA3B Antibody [CELA3B/1758]
Description
Mouse monoclonal [CELA3B/1758] antibody to CELA3B.
Specificity
This antibody recognizes a protein of ~30kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function.
Applications
ELISA
Dilutions
WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 82-238, of human CELA3B protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
CELA3B/1758
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
~17 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CELA3B Antibody [CELA3B/1758] - BSA and Azide free (A251782).
Synonyms
Chymotrypsin like elastase family member 3B, ELA3B, Elastase 3B, Elastase IIIB, Protease E
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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