Mouse monoclonal [PCRP-CDC5L-2C6] antibody to CDC5L.
Specificity
Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3q13.1) with USF-2.
Applications
Flow Cytometry, IHC-P
Positive Control
HeLa cells. Ubiquitously expressed in both fetal and adult tissues.