Anti-CD55 Antibody [Bu14] (FITC) (A279875)

$420

Mouse monoclonal [Bu14] antibody to CD55 (FITC) for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD55 Antibody [Bu14] (FITC)
Description
Mouse monoclonal [Bu14] antibody to CD55 (FITC).
Specificity
This antibody recognises human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway.The molecular weight of CD55 varies between ~50 and 100 kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid. CD55 acts as a ligand for CD97 and is an entry receptor for Echovirus and Coxsackie B virus. CD55 has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: Neat - 1:20, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone ID
Bu14
Isotype
IgG1
Conjugate

FITC

Excitation: 490nm, Emission: 525nm

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
100 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
General Notes
Mouse anti Human CD55 antibody, clone Bu14 recognizes human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway.The molecular weight of CD55 varies between ~50 and 100 kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid (Medof et al. 1987).CD55 acts as a ligand for CD97 (Hamaan et al. 1998) and is an entry receptor for Echovirus (Bergelson et al. 1994) and Coxsackie B virus (Hafenstein et al. 2007). CD55 has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development (Visser et al. 2002).
Synonyms
CD 55, CD55 antigen, CD55 Cromer blood group system, CD55 molecule, CD55 molecule (Cromer blood group), CD55 molecule, decay accelerating factor for complement (Cromer blood group), Cd55a, Complement decay accelerating factor, Complement decay-accelerating factor, Complement decay-accelerating factor, GPI-anchored, CR, CROM, Cromer Blood Group antigen, Cromer blood group system, DAF, Daf-GPI, Daf1, DAF_HUMAN, Dcay accelerating factor for complement (CD55, Cromer blood group system), Decay accelarating factor 1, isoform CRA_a, Decay accelerating factor (GPI-form), Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF, TC
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-CD55 Antibody [Bu14] (FITC) (A279875)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-CD55 Antibody [Bu14] (FITC) (A279875)

Top