Anti-CD45RB Antibody [MEM-143] (A85474)

Anti-CD45RB Antibody [MEM-143]

Mouse monoclonal [MEM-143] antibody to CD45RB.

This antibody reacts with a protein determinant of CD45RB, a 180-240 kDa single chain type I membrane glycoprotein, variant of CD45 (CD45RB isoform). CD45RB is expressed on a subset of T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. The MEM-143 is therefore not neuraminidase sensitive like most other anti-CD45RB antibodies (including standard antibody MEM-55). The reactivity of the antibody MEM-143 can be blocked by a peptide including amino acids 79-88.

Flow Cytometry, IHC-P

Flow Cytometry: 0.5-4 µg/ml. The staining pattern of the MEM-143 shows prominent differences from other anti-CD45RB reagents including standard antibody MEM-55, mostly as a result of the recognition of differences in glycosylation, IHC-P: 10 µg/ml; Positive Control: human tonsil.

Human

Human peripheral blood lymphocytes.

Mouse

Monoclonal

MEM-143

IgG1

Protein A chromatography.

1 mg/ml

180-240 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

B220, CD 45, CD45, CD45 antigen, CD45R, GP180, L-CA, LCA, Leukocyte common antigen, LY5, Lyt4, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase, receptor type, c polypeptide, Ptprc, PTPRC_HUMAN, Receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen