Recombinant Anti-CD43 Antibody [SPN/6562R] - BSA and Azide free (A278654)

Recombinant rabbit monoclonal [SPN/6562R] antibody to CD43 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD43 Antibody [SPN/6562R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [SPN/6562R] antibody to CD43.
Specificity
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human CD43 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
SPN/6562R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
1 mg/ml
Molecular Weight
95 kDa / 115 kDa / 135 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD43 Antibody [SPN/6562R] (A278066).
Synonyms
CD 43, CD43 antigen, Galactoglycoprotein, GALGP, GPL 115, GPL115, Human gene for sialophorin, Leucocyte sialoglycoprotein, Leukocyte large sialoglycoprotein, Leukocyte sialoglycoprotein, Leukosialin, LEUK_HUMAN, LSN, Ly-48, Sialophorin, sialophorin (gpL115, leukosialin, CD43), Spn
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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