Anti-CD4 Antibody [b38c6c7] (A279769)

Anti-CD4 Antibody [b38c6c7]

Mouse monoclonal [b38c6c7] antibody to CD4.

This antibody recognises a ~55 kDa porcine homologue of the human CD4 antigen found on the surface of T helper cells. Clone b38c6c7 was confirmed to bind to a member of the CD4 alpha cluster at the ‘Third International Workshop on Swine Leukocyte Differentiation Antigens’. Porcine CD4 is a type 1 transmembrane member of the immunoglobulin superfamily. Pigs are unusual among mammalian species as they appear to have four populations of resting T lymphocytes. In addition to CD4+/CD8- and CD4-/CD8+ lymphocytes they also appear to have significant populations of CD4-/CD8- and CD4+/CD8+ cells. Lymphoblasts with a double positive phenotype have been described in other species but not in the case of mature peripheral T cells.

Flow Cytometry: Neat - 1:50, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Porcine

Porcine leukocytes.

Mouse

Monoclonal

b38c6c7

IgG1

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Porcine CD4, clone b38c6c7 recognizes a ~55 kDa porcine homologue of the human CD4 antigen found on the surface of T helper cells. Clone b38c6c7 was confirmed to bind to a member of the CD4 alpha cluster at the ‘Third International Workshop on Swine Leukocyte Differentiation Antigens’ (Haverson et al. 2001).Porcine CD4 is a type 1 transmembrane member of the immunoglobulin superfamily. Pigs are unusual among mammalian species as they appear to have four populations of resting T lymphocytes. In addition to CD4+/CD8- and CD4-/CD8+ lymphocytes they also appear to have significant populations of CD4-/CD8- and CD4+/CD8+ cells. Lymphoblasts with a double positive phenotype have been described in other species but not in the case of mature peripheral T cells (Saalmuller et al. 1987).

CD 4, CD4 (L3T4), CD4 antigen, CD4 antigen (p55), CD4 molecule, CD4 receptor, CD4+ Lymphocyte deficiency, included, CD4mut, CD4_HUMAN, L3T4, Leu3, Ly-4, Lymphocyte antigen CD4, MGC165891, OTTHUMP00000238897, p55, T cell antigen T4, T cell antigen T4/LEU3, T cell differentiation antigen L3T4, T cell OKT4 deficiency, included, T cell surface antigen T4/Leu 3, T cell surface antigen T4/Leu3, T cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, W3/25, W3/25 antigen