Anti-CD35 Antibody [To5] - BSA and Azide free (A251442)

Name: Anti-CD35 Antibody [To5] - BSA and Azide free
Brand: Antibodies.com
SKU: A251442
Price: 525.0 USD
Availability: InStock

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$525

Mouse monoclonal [To5] antibody to CD35 for Flow Cytometry, IF and IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

Contact Us

Telephone

+1 (314) 370-6046

orders@antibodies.com

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Specifications

Name

Anti-CD35 Antibody [To5] - BSA and Azide free

Description

Mouse monoclonal [To5] antibody to CD35.

Specificity

This antibody recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

Applications

Flow Cytometry, IF, IHC-P

Dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivity

Human

Immunogen

Recombinant human CR1 protein.

Host

Mouse

Clonality

Monoclonal

Clone ID

To5

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Molecular Weight

210-220 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD35 Antibody [To5] (A248260).

Synonyms

C3 binding protein, C3b/C4b receptor, C3BR, C4BR, CD 35, CD35 antigen, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3b/4b) receptor 1 including Knops blood group system, Complement component receptor 1, Complement receptor 1, Complement receptor type 1, CR 1, CR1, CR1_HUMAN, KN, Knops blood group antigen

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (2)

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Figure 1: Immunohistochemistry - Anti-CD35 Antibody [To5] - BSA and Azide free (A251442)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil using Anti-CD35 Antibody [To5].

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Figure 2: SDS-PAGE - Anti-CD35 Antibody [To5] - BSA and Azide free (A251442)

SDS-PAGE analysis of Anti-CD35 Antibody [To5] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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