Anti-CD30 Antibody [Ber-H2 + CD30/412] (A254290)

Anti-CD30 Antibody [Ber-H2 + CD30/412]

Mouse monoclonal [Ber-H2 + CD30/412] antibody to CD30.

This antibody recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

IHC-P: 1:100-1:200

Human

Clone Ber-H2: Co cell line established from a patient with Hodgkin's disease of T-cell lineage. Clone CD30/412: Recombinant human CD30 protein.

Mouse

Oligoclonal

Ber-H2 + CD30/412

Unconjugated

105-120 kDa

Tissue culture supernatant.

Liquid

Supplied as an aliquot of tissue culture supernatant with 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

CD 30, CD30 antigen, CD30L receptor, Cytokine receptor CD30, D1S166E, KI 1, KI 1 antigen, Ki-1 antigen, KI1, Lymphocyte activation antigen CD30, TNFRSF 8, Tnfrsf8, TNR8_HUMAN, Tumor necrosis factor receptor superfamily member 8