Recombinant Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free (A251444)

Name: Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free
Brand: Antibodies.com
SKU: A251444
Price: 525.0 USD
Availability: InStock

Enlarge Image

$525

Recombinant mouse monoclonal [rCR2/1952] antibody to CD21 for IHC-P.

100% Guarantee

Price Match Guarantee

Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

Contact Us

Telephone

+1 (314) 370-6046

orders@antibodies.com

Guarantees

100% Quality Guarantee

Price Match Guarantee

Tags:

Recombinant Antibody

Specifications

Name

Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free

Description

Recombinant mouse monoclonal [rCR2/1952] antibody to CD21.

Specificity

This antibody recognizes a protein of 140kDa, which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Applications

IHC-P

Dilutions

IHC-P: 1-2 µg/ml

Reactivity

Human

Immunogen

Recombinant fragment, around amino acids 44-196, of human CD21, protein. The exact sequence is proprietary.

Host

Mouse

Clonality

Monoclonal

Clone ID

rCR2/1952

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Molecular Weight

140 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD21 Antibody [rCR2/1952] (A248262).

Synonyms

C3DR, CD 21, Complement C3d receptor, Complement C3d receptor 2, Complement component (3d/Epstein Barr virus) receptor 2, Complement receptor type 2, CR, Cr2, CR2_HUMAN, CVID7, EBV receptor, EBV-R, Epstein Barr virus receptor, Epstein-Barr virus receptor, EVBR, SLEB9

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

Enlarge Image

Figure 1: Immunohistochemistry - Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free (A251444)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human spleen using Anti-CD21 Antibody [rCR2/1952].

Enlarge Image

Figure 2: Immunohistochemistry - Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free (A251444)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human spleen using Anti-CD21 Antibody [rCR2/1952].

Enlarge Image

Figure 3: SDS-PAGE - Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free (A251444)

SDS-PAGE analysis of Anti-CD21 Antibody [rCR2/1952] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

Publishing research using Recombinant Anti-CD21 Antibody [rCR2/1952] - BSA and Azide free (A251444)? Please let us know so that we can list the citation on this page.