Anti-CD204 Antibody [2F8] (A279222)

$145

Rat monoclonal [2F8] antibody to CD204 for WB, IP, Flow Cytometry, IHC-Fr and ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD204 Antibody [2F8]
Description
Rat monoclonal [2F8] antibody to CD204.
Specificity
This antibody recognises the murine scavenger receptor class A (SR-A), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. recognises an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Rat anti Mouse CD204 antibody, clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
Applications
WB, IP, Flow Cytometry, IHC-Fr, ELISA
Dilutions
Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Mouse, Pig, Channel catfish
Immunogen
Raw 264 cell line.
Host
Rat
Clonality
Monoclonal
Clone ID
2F8
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rat anti Mouse CD204 antibody, clone 2F8 recognizes the murine scavenger receptor class A (SR-A), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. Rat anti Mouse CD204 antibody, clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion (Fraser et al. 1993). Rat anti Mouse CD204 antibody, clone 2F8 recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Rat anti Mouse CD204 antibody, clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain (Daugherty et al. 2000).
Synonyms
CD204 antigen, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor 1, Macrophage Scavenger Receptor I, Macrophage scavenger receptor type III, Macrophage scavenger receptor types I and II, Msr 1, MSR1, MSRE_HUMAN, phSR1, phSR2, SCARA 1, SCARA1, Scavenger receptor class A member 1, Scavenger receptor class A, member 1, Scavenger receptor type A, Scvr, SR A, SRA
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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