Mouse monoclonal [CD163L1/7974] antibody to CD163L1.
Specificity
CD163L1 (CD163 molecule-like 1), also known as scavenger receptor cysteinerich type 1 protein M160 or CD163B, is a 1,453 amino acid protein that belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. Members of the SRCR family contain SRCR domains which are used to influence ligand binding and protein-protein interaction, and are found in cells of the immune system where they exist as membrane-anchored or secreted proteins. Containing 12 SRCR domains, CD163L1 undergoes alternative splicing events to produce 3 isoforms. CD163L1 isoforms 1 and 2 are single-pass type I membrane proteins, unlike isoform 3, which is a secreted protein. CD163L1 isoform 1 is abundantly expressed in lymph node, spleen, thymus and fetal liver, and isoform 2 is found exclusively in spleen. The gene encoding CD163L1 maps to human chromosome 12p13.31.
Applications
IHC-P
Positive Control
Human lymphoid tissue.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment of human CD163L1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
CD163L1/7974
Isotype
IgG
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
159 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
