Anti-CD147 Antibody [BSG/7952] (A314594)

Anti-CD147 Antibody [BSG/7952]

Mouse monoclonal [BSG/7952] antibody to CD147.

This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

WB, IHC-P

THP-1 or HSB2 cells. Human renal cell carcinoma, ovarian carcinoma or melanoma.

WB: 1-2 µg/ml, IHC: 0.5-1 µg/ml

Human

Recombinant full-length human BSG protein.

Mouse

Monoclonal

BSG/7952

IgG

Protein A/G chromatography.

200 µg/ml

35 kDa (non-reduced) / 40 kDa (reduced)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

5A11 antigen, 5F7, Basigin, Basigin (Ok blood group), BASI_HUMAN, Blood brain barrier HT7 antigen, Bsg, CD 147, CD147 antigen, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, M 6, M6, M6 leukocyte activation antigen, Neurothelin, OK, OK blood group, OK blood group antigen, TCSF, Tumor cell derived collagenase stimulatory factor, Tumor cell-derived collagenase stimulatory factor