Anti-CD137 Antibody [JG1.6A] (A280776)

Anti-CD137 Antibody [JG1.6A]

Rat monoclonal [JG1.6A] antibody to CD137.

This antibody recognises human CD137, an 83kD type I integral membrane protein, otherwise known as 4-1BB. The CD137 molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumour necrosis receptor family and regulates T-cell activation and proliferation.Rat anti Human CD137 antibody, clone JG1.6A induces ?-interferon activity in isolated T-cells as measured by ELISA.

Flow Cytometry, ELISA

Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Recombinant human CD137-Fc.

Rat

Monoclonal

JG1.6A

IgG2a

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

Liquid

Supplied in TRIS Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Human CD137 antibody, clone JG1.6A recognizes human CD137, an 83kD type I integral membrane protein, otherwise known as 4-1BB. The CD137 molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumour necrosis receptor family and regulates T-cell activation and proliferation.Rat anti Human CD137 antibody, clone JG1.6A induces ?-interferon activity in isolated T-cells as measured by ELISA (Rajendran et al. 2019).

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