Anti-CCL14 Antibody [B02-1G7] (Biotin) (A279727)

Anti-CCL14 Antibody [B02-1G7] (Biotin)

Mouse monoclonal [B02-1G7] antibody to CCL14 (Biotin).

This antibody recognises C-C motif chemokine 14, also known as HCC1 and NCC-2. CCL14 is a CC-type chemokine which is constitutively expressed in many tissues , and present at very high concentrations in normal human plasma. This chemokine is involved with activation of immune cells, promoting chemotaxis of monocytes, eosinophils, and T lymphoblasts. CCL14 is involved with pathogenesis of allergic airway inflammation and some cancers. It has been identified as a prognostic biomarker in hepatocellular carcinoma, where it modules the cell cycle and promotes apoptosis. The biotinylated Mouse anti Human CCL14 antibody, clone B02-1G7 (MCA6179B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL14 antibody, clone B12-1D8 (MCA6178GA) as the capture antibody.

ELISA: 1 µg/ml

Human

E. coli derived recombinant human CCL14 (Thr20-Asn93).

Mouse

Monoclonal

B02-1G7

IgG1

Protein G affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human CCL14 antibody, clone B02-1G7, recognizes C-C motif chemokine 14, also known as HCC1 and NCC-2. CCL14 is a CC-type chemokine which is constitutively expressed in many tissues (Gu et al. 2020), and present at very high concentrations in normal human plasma (Savino et al. 2009). This chemokine is involved with activation of immune cells, promoting chemotaxis of monocytes, eosinophils, and T lymphoblasts. CCL14 is involved with pathogenesis of allergic airway inflammation and some cancers. It has been identified as a prognostic biomarker in hepatocellular carcinoma, where it modules the cell cycle and promotes apoptosis (Zhu et al. 2019). The biotinylated Mouse anti Human CCL14 antibody, clone B02-1G7 (MCA6179B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL14 antibody, clone B12-1D8 (MCA6178GA) as the capture antibody.

C-C motif chemokine 14, Chemokine CC-1/CC-3, HCC-1(1-74, HCC-1/HCC-3, NCC-2, NCC2, SCYA14, Small-inducible cytokine A14

This product is for research use only. It is not intended for diagnostic or therapeutic use.