Acts as antagonist using an in vitro bioassay in PDF-P1 3B9 cells stably transfected with rabbit GH receptors. It is capable of forming a 1:1 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD) and binds to this ECD with affinity similar the the wild type oGH.
Purity
>98% as determined by RP-HPLC, Gel Filtration, and SDS-PAGE.
Product Form
Lyophilized
Concentration
1 mg/ml
Formulation
Lyophilized from a solution containing 4.5 µM Sodium Bicarbonate, pH 9.
Storage
Shipped at ambient temperature. Lyophilized: Short term (2 weeks) store at 25°C. Long term store below -18°C. Reconstituted and filter sterilization: Short term (4 weeks) store at 4°C. Long term store below -18°C, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze/thaw cycles.