This protein is constructed from the following P Glycoprotein sequences: (Phe72-Arg113) (Lys213-Thr215) (Thr318-Gln330) (Gly960-Asp973). The human Fc tag consists of amino acids Glu99-Ala330.
The protein has a predicted molecular mass of 34.2 kDa after removal of the signal peptide. The apparent molecular mass of MDR-1-hFc is approximately 25-55 kDa due to glycosylation.
Conjugate
Unconjugated
Purity
> 95% by SDS-PAGE and Coomassie blue staining.
Product Form
Lyophilized
Concentration
Reconstitution dependent.
Formulation
Lyophilized from sterile Phosphate Buffered Saline, pH 7.4. Normally 5%–8% Trehalose is added as a protectant before lyophilization.
Storage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
Synonyms
ABCB1, ATP-binding cassette sub-family B member 1, ATP-dependent translocase ABCB1, CD243, EC:7.6.2.2, MDR1, Multidrug resistance protein 1, P-glycoprotein 1, PGY1, Phospholipid transporter ABCB1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
SDS-PAGE - Recombinant Human P Glycoprotein Protein (Fc Tag) (A318152)
Recombinant Human P Glycoprotein Protein (Fc Tag) (A318152) on SDS-PAGE under reducing conditions.
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