Recombinant Human DR5 Protein (A61503)

Overview
Specifications

Shipping Information

Freight/Packing Charges: $40

Dispatched from St. Louis, MO.

Lead Time: 5-8 business days.

Tags:

Biologically Active

Specifications

Name

Recombinant Human DR5 Protein

Applications

SDS-PAGE

Expression System

Escherichia coli

Nature

Recombinant

Protein Species

Human

Protein Length

Protein fragment

Sequence

ESALITQQD LAPQQRVAPQ QKRSSPSEGL CPPGHHISED GRDCISCKYG QDYSTHWNDL LFCLRCTRCD SGEVELSPCT TTRNTVCQCE EGTFREEDSP EMCRKCRTGC PRGMVKVGDC TPWSDIECVH KES

Predicted MW

14.8 kDa

Biologically Active

Yes

Biological Activity

The TNFRSF10B reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/ml) but in the presence of TNFRSF10B, TRAIL-induced TNF is suppressed.

Purity

>95% as determined by SDS-PAGE.

Product Form

Lyophilized

Concentration

Reconstitution dependent.

Formulation

Lyophilized from Phosphate Buffered Saline, pH 7.4.

Storage

Shipped at ambient temperature. Lyophilized: Short term (3 weeks) store at 25°C. Long term store desiccated below -18°C. Reconstituted: Short term (2-7 days) store at 4°C. Long term store below -18°C, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze/thaw cycles.

Synonyms

CD262, Death receptor 5, KILLER, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAILR2, TRICK2, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Publishing research using Recombinant Human DR5 Protein (A61503)? Please let us know so that we can list the citation on this page.

Alternative products to Recombinant Human DR5 Protein (A61503)

A113767

Recombinant Human DR5 Protein (C-terminal His Tag)

Validated for SDS-PAGE.