Anti-YY1 Antibody [YY1/5436] (A315796)

Anti-YY1 Antibody [YY1/5436]

Mouse monoclonal [YY1/5436] antibody to YY1.

The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3E1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.

WB, IHC-P

Human kidney, tonsil or cervix carcinoma tissues

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

His-tagged YY1 protein.

Mouse

Monoclonal

YY1/5436

kappa

Protein A/G chromatography.

200 µg/ml

40 kDa / 68 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Delta transcription factor, INO80 complex subunit S, INO80S, NF-E1, Transcriptional repressor protein YY1, Yin and yang 1, YY-1