Anti-XIAP Antibody (A283968)

Anti-XIAP Antibody

Rabbit polyclonal antibody to XIAP.

This antibody recognises human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). Regulators of XIAP activity include XAF-1 and Smac. Rabbit anti Human XIAP antibody detects a band of approximately 57 kDa in human kidney lysates.

WB, IHC-P

IHC-P 1: 2 µg/ml, WB: 0.5 µg/ml - 2 µg/ml

Human, Mouse

Synthetic peptide corresponding to 13 amino acids within the C-terminus of human XIAP.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human XIAP antibody recognizes human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs).Regulators of XIAP activity include XAF-1 and Smac. Rabbit anti Human XIAP antibody detects a band of approximately 57 kDa in human kidney lysates.

API3, Baculoviral IAP repeat-containing protein 4, BIRC4, E3 ubiquitin-protein ligase XIAP, hIAP-3, hIAP3, hILP, IAP-3, IAP-like protein, IAP3, ILP, Inhibitor of apoptosis protein 3, RING-type E3 ubiquitin transferase XIAP, X-linked IAP, X-linked inhibitor of apoptosis protein