Recombinant Anti-Vinculin Antibody [VCL/7091R] - BSA and Azide free (A278664)

Recombinant rabbit monoclonal [VCL/7091R] antibody to Vinculin for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-Vinculin Antibody [VCL/7091R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [VCL/7091R] antibody to Vinculin.
Specificity
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and α-Actinin. In addition, vinculin, Talin and α-Actinin each contain Actin binding sites. Expression of vinculin and Talin have been shown to be affected by the level of Actin expression. α-Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.
Applications
WB, IHC-P
Dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human, Mouse
Immunogen
Recombinant fragment, around amino acids 174-322, of human Vinculin protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
VCL/7091R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
117 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Vinculin Antibody [VCL/7091R] (A278076).
Synonyms
Metavinculin, MV, VCL
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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