Anti-VEGFA Antibody [CD19-4G11] (Biotin) (A280084)

Anti-VEGFA Antibody [CD19-4G11] (Biotin)

Mouse monoclonal [CD19-4G11] antibody to VEGFA (Biotin).

This antibody recognises vascular endothelial growth factor alpha (VEGF-A) which forms a homodimer and is a potent stimulator of angiogenesis of both normal and cancerous cells. It acts as a regulator of vasculogenesis, angiogenesis and endothelial cell growth. VEGF-A is secreted by many different cell types such as endothelial cells , smooth muscle cells , neutrophils , platelets , macrophages and 60% of all tumors. The biotinylated Mouse anti Human VEGF antibody, clone CD19-4G11 (MCA6287B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human VEGF antibody, clone CD17-1E1 (MCA6286GA) as the capture antibody.

ELISA: 1 µg/ml

Human

E. coli derived recombinant full length human VEGF (Ala27-Arg147).

Mouse

Monoclonal

CD19-4G11

IgG1

Protein G affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human VEGF antibody, clone CD19-4G11, recognizes vascular endothelial growth factor alpha (VEGF-A) which forms a homodimer and is a potent stimulator of angiogenesis of both normal and cancerous cells. It acts as a regulator of vasculogenesis, angiogenesis and endothelial cell growth. VEGF-A is secreted by many different cell types such as endothelial cells (Nissen et al. 1998), smooth muscle cells (Brogi et al. 1994), neutrophils (Gaudry et al. 1997), platelets (Banks et al. 1998), macrophages and 60% of all tumors (Berse et al. 1992). The biotinylated Mouse anti Human VEGF antibody, clone CD19-4G11 (MCA6287B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human VEGF antibody, clone CD17-1E1 (MCA6286GA) as the capture antibody.

L-VEGF, Vascular endothelial growth factor A, long form, Vascular permeability factor, VEGF, VPF

This product is for research use only. It is not intended for diagnostic or therapeutic use.