Anti-VEGF Antibody [VEGF/1063] (A250292)

Anti-VEGF Antibody [VEGF/1063]

Mouse monoclonal [VEGF/1063] antibody to VEGF.

This antibody recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

IHC-P: 4-8 µg/ml

Human, Mouse, Rat, Rabbit, Canine

Recombinant human VEGF189 protein.

Mouse

Monoclonal

VEGF/1063

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

19-22 kDa (reducing) / 38 kDa-44 kDa (non-reducing)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-VEGF Antibody [VEGF/1063] - BSA and Azide free (A253472).

L-VEGF, Vascular endothelial growth factor A, long form, Vascular permeability factor, VPF