Anti-Tyrosine Hydroxylase Antibody (A283964)

Anti-Tyrosine Hydroxylase Antibody

Rabbit polyclonal antibody to Tyrosine Hydroxylase.

This antibody recognises tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain.Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

WB, IHC-P, IHC-Fr, IF

IF: 1:1,000, IHC-Fr: 1:1,000, WB: 1:1,000

Rat, Mammals, Grasshopper (Gastrimargus musicus), Rat, Mouse

Tyrosine hydroxylase purified from pheochromocytoma.

Rabbit

Polyclonal

IgG

Approximately 60 kDa in rat caudate cell lysates.

Liquid

Supplied in 10mM HEPES, pH 7.5, with 0.01% BSA, 50% Glycerol, and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Rat tyrosine hydroxylase antibody recognizes tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease (Haavik et al. 1998).

TH, TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase