Anti-Transferrin Receptor Antibody [23D10] (A279141)

Anti-Transferrin Receptor Antibody [23D10]

Mouse monoclonal [23D10] antibody to Transferrin Receptor.

This antibody recognises human soluble CD71 (also known as transferrin receptor, or TfR). CD71 is a homodimeric membrane protein, approximately 90 kDa in size. It is responsible for the uptake of iron into the cell, by binding to and internalising iron-bound transferrin (ferrotransferrin). After the iron is released into the cell, the apotransferrin is relocated to the cell surface and released into the circulation. When CD71 is cleaved at Arg-100, a soluble (or serum) form of the protein is released. The level of soluble CD71 is used to detect erythropoietin misuse by athletes. It is also used to diagnose iron deficiency anemia. recognises human soluble transferrin receptor and the complex between soluble transferrin receptor and transferrin.

WB, ELISA

Human

Purified human soluble transferrin receptor.

Mouse

Monoclonal

23D10

IgG2b

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human CD71 (Soluble) antibody, clone 23D10 recognizes human soluble CD71 (also known as transferrin receptor, or TfR). CD71 is a homodimeric membrane protein, approximately 90 kDa in size. It is responsible for the uptake of iron into the cell, by binding to and internalising iron-bound transferrin (ferrotransferrin). After the iron is released into the cell, the apotransferrin is relocated to the cell surface and released into the circulation. When CD71 is cleaved at Arg-100, a soluble (or serum) form of the protein is released. The level of soluble CD71 is used to detect erythropoietin misuse by athletes. It is also used to diagnose iron deficiency anemia. Mouse anti Human CD71 (Soluble) antibody, clone 23D10 recognizes human soluble transferrin receptor and the complex between soluble transferrin receptor and transferrin.

CD71, p90, T9, TfR, TfR1, TFRC, TR, Transferrin receptor protein 1, Trfr