Anti-Topoisomerase II alpha Antibody [rTOP2A/8339]
Description
Recombinant mouse monoclonal [rTOP2A/8339] antibody to Topoisomerase II alpha.
Specificity
It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.
Applications
IHC-P
Positive Control
HeLa or Jurkat cells. Human lymph node or tonsil.
Dilutions
IHC: 0.5-1 µg/ml
Reactivity
Human
Immunogen
Recombinant human Topoisomerase II alpha fragment (aa1300-1500). The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
rTOP2A/8339
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
170 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, TOP2
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Recombinant Anti-Topoisomerase II alpha Antibody [rTOP2A/8339] (A315742)? Please let us know so that we can list the citation on this page.
Alternative products to Anti-Topoisomerase II alpha Antibody [rTOP2A/8339] (A315742)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1361] (A250168) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250168_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1361] - BSA and Azide free (A253348) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253348_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1362] - BSA and Azide free (A253349) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253349_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1362] (A250169) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250169_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6569] (A277925) - Antibodies.com](https://cdn.antibodies.com/image/catalog/277/A277925_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6569] - BSA and Azide free (A278513) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278513_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/6570R] (A278072) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278072_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/6570R] - BSA and Azide free (A278660) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278660_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6629] (A250170) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250170_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6629] - BSA and Azide free (A253350) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253350_1.jpg?profile=product_alternative)