Rabbit polyclonal antibody to TOP2A (Phospho-Ser1106)
Specificity
The antibody detects endogenous levels of TOP2A only when phosphorylated at serine 1106.
Applications
WB, IHC
Reactivity
Human, Mouse
Immunogen
Peptide sequence around phosphorylation site of serine 1106 (E-E-S(p)-D-N) derived from Human TOP2A.
Host
Rabbit
Clonality
Polyclonal
Conjugate
Unconjugated
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/ml
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage
Store at -20˚C
Synonyms
DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, TOP2
Western blot analysis of extracts from Jurkat cells, treated with paclitaxel (1uM, 24hours), using TOP2A (Phospho-Ser1106) antibody #12110. The lane on the right is treated with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TOP2A (Phospho-Ser1106) antibody #12110. The picture on the right is treated with the synthesized peptide.
Publishing research using Anti-TOP2A (Phospho-Ser1106) Antibody (A50409)? Please let us know so that we can list the citation on this page.
Alternative products to Anti-TOP2A (Phospho-Ser1106) Antibody (A50409)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1361] (A250168) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250168_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1361] - BSA and Azide free (A253348) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253348_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1362] (A250169) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250169_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/1362] - BSA and Azide free (A253349) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253349_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/6570R] (A278072) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278072_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [TOP2A/6570R] - BSA and Azide free (A278660) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278660_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6569] (A277925) - Antibodies.com](https://cdn.antibodies.com/image/catalog/277/A277925_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6569] - BSA and Azide free (A278513) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278513_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Topoisomerase II alpha Antibody [rTOP2A/6629] (A250170) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250170_1.jpg?profile=product_alternative)