General Notes
Mouse anti Human CD282 antibody, clone 11G7 recognizes the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (Sandor et al. 2003). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.