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Recombinant Anti-TIMP1 Antibody [TIMP1/1944R] (A250132)

Recombinant rabbit monoclonal [TIMP1/1944R] antibody to TIMP1 for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-TIMP1 Antibody [TIMP1/1944R]
Description
Recombinant rabbit monoclonal [TIMP1/1944R] antibody to TIMP1.
Specificity
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes.
Applications
ELISA
Reactivity
Human
Immunogen
Recombinant full-length human TIMP1 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
TIMP1/1944R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
200 µg/ml
Molecular Weight
23 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TIMP1 Antibody [TIMP1/1944R] - BSA and Azide free (A253312).
Synonyms
CLGI, Collagenase inhibitor, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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