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Anti-TIMP1 Antibody [2A5] - BSA and Azide free (A253310)

Mouse monoclonal [2A5] antibody to TIMP1 for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-TIMP1 Antibody [2A5] - BSA and Azide free
Description
Mouse monoclonal [2A5] antibody to TIMP1.
Specificity
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes.
Applications
ELISA
Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids 72-82 of human TIMP1 protein.
Sequence
FQALGDAADIR
Host
Mouse
Clonality
Monoclonal
Clone ID
2A5
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
1 mg/ml
Molecular Weight
23 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-TIMP1 Antibody [2A5] (A250130).
Synonyms
CLGI, Collagenase inhibitor, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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