Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!
Formulation
Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.
Storage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
Synonyms
AXL oncogene, Tyrosine-protein kinase receptor UFO, UFO
SDS-PAGE analysis of Tilvestamab Biosimilar - Anti-Axl Antibody - Low endotoxin, Azide free (A323784) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.
SEC-HPLC analysis of Tilvestamab Biosimilar - Anti-Axl Antibody - Low endotoxin, Azide free (A323784) confirms that the purity of this antibody is greater than 95%.
Immobilized recombinant human Axl protein (Fc tag) at 2 µg/ml is bound by Tilvestamab Biosimilar - Anti-Axl Antibody - Low endotoxin, Azide free (A323784). EC50 = 0.01542 µg/ml.
Human AXL HEK293 cells were stained with Tilvestamab Biosimilar - Anti-Axl Antibody - Low endotoxin, Azide free (A323784) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50 = 0.07318 µg/ml.
The endocytosis ratio of Tilvestamab Biosimilar - Anti-Axl Antibody - Low endotoxin, Azide free (A323784) by U251 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40% at antibody concentration of 1 nM.
Tilvestamab Biosimilar - Anti-Axl Antibody - Low endotoxin, Azide free (A323784) P-AKT Test was evaluated using U251 cell. The max induction fold was approximately 1.43.
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