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Recombinant Anti-Thrombomodulin Antibody [THBD/8188R] (A315725)

$790

Recombinant rabbit monoclonal [THBD/8188R] antibody to Thrombomodulin for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-Thrombomodulin Antibody [THBD/8188R]
Description
Recombinant rabbit monoclonal [THBD/8188R] antibody to Thrombomodulin.
Specificity
It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Applications
IHC-P
Positive Control
Placenta, Angiosarcoma, Bladder or Cervical Carcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human Thrombomodulin (CD141) protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
THBD/8188R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
~100 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
CD141, Fetomodulin, THBD, THRM, TM
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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