Anti-TAPA1 Antibody [1.3.3.22] (A250802)

Anti-TAPA1 Antibody [1.3.3.22]

Mouse monoclonal [1.3.3.22] antibody to TAPA1.

This antibody recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Functional Studies, Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 2-4 µg/ml

Human, Mouse, Rat

Recombinant full-length human CD81 protein.

Mouse

Monoclonal

1.3.3.22

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

26 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TAPA1 Antibody [1.3.3.22] - BSA and Azide free (A253982).

26 kDa cell surface protein TAPA-1, CD81 antigen, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28, TSPAN28