Recombinant Anti-Synaptophysin Antibody [rSYP/4654] (A250072)

Anti-Synaptophysin Antibody [rSYP/4654]

Recombinant mouse monoclonal [rSYP/4654] antibody to Synaptophysin.

This antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 224-313, of human Synaptophysin protein. The exact sequence is proprietary.

Mouse

Monoclonal

rSYP/4654

IgG2a

kappa

Protein A/G chromatography.

200 µg/ml

38 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Synaptophysin Antibody [rSYP/4654] - BSA and Azide free (A253252).

Major synaptic vesicle protein p38, SYP