Anti-Superoxide Dismutase 1 Antibody [2F5] (A279213)

Anti-Superoxide Dismutase 1 Antibody [2F5]

Mouse monoclonal [2F5] antibody to Superoxide Dismutase 1.

This antibody recognises bovine superoxide dismutase (Cu/Zn), also known by it's gene name SOD1. Bovine superoxide dismutase (Cu/Zn) is a 152 amino acid ~15kDa cytoplasmic protein involved in the removal of free radicals from the cytosol. Superoxide dismutases are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor: Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel. Mouse anti Bovine superoxide dismutase (Cu/Zn) antibody, clone 2F5 does not cross react with immunoglobulins but does react weakly with Mn SOD.

IHC-P, IHC-Fr, ELISA

This product does not require pre-treatment of paraffin embedded sections e.g. trypsin or pronase prior to staining. This product does not require antigen retrieval using heat treatment methods prior to staining of paraffin sections.

Bovine, Human, Mouse

Superoxide dismutase enzyme prepared from bovine erythrocytes.

Mouse

Monoclonal

2F5

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% BSA and 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Bovine superoxide dismutase (Cu/Zn) antibody, clone 2F5 recognizes bovine superoxide dismutase (Cu/Zn), also known by it's gene name SOD1. Bovine superoxide dismutase (Cu/Zn) is a 152 amino acid ~15kDa cytoplasmic protein involved in the removal of free radicals from the cytosol. Superoxide dismutases are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor: Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel.Mouse anti Bovine superoxide dismutase (Cu/Zn) antibody, clone 2F5 does not cross react with immunoglobulins but does react weakly with Mn SOD.

hSod1, Superoxide dismutase [Cu-Zn]