Anti-smooth muscle Myosin heavy chain 11 Antibody [SM-M10] (A315657)

Anti-smooth muscle Myosin heavy chain 11 Antibody [SM-M10]

Mouse monoclonal [SM-M10] antibody to smooth muscle Myosin heavy chain 11.

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Flow Cytometry, IF, IHC-P

Uterus or normal breast.

Flow Cytometry: 0.5-1 µg/million cells, IF: 0.5-1 µg/ml, IHC: 1-2 µg/ml

Human, Bovine, Mouse

Crude human uterus extract.

Mouse

Monoclonal

SM-M10

kappa

Protein A/G chromatography.

200 µg/ml

205 kDa (MHC-1) / 200 kDa (MHC-2)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.